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The Natural “Ozempic”? How a Bitter Hop Compound Crushes Cravings with Sarah Kennedy, CEO of Calocurb

The Natural “Ozempic”? How a Bitter Hop Compound Crushes Cravings with Sarah Kennedy, CEO of Calocurb

Sarah Kennedy, CEO of Calocurb, joins me to explore the science of appetite regulation, hormone health, and why bitter plant compounds may be the key to modern weight challenges.

We unpack the fascinating 15-year research journey that began with a $30M government grant in New Zealand and led to the discovery of a specific hop variety that increases satiety hormones by 600%. Sarah contrasts Calocurb with drugs like Ozempic, sharing why a natural, hormone-supportive approach could be the future of weight management.

From PMS cravings to perimenopause, from post-Ozempic rebound hunger to late-night snacking, Sarah explains how Calocurb works with your body rather than against it.

We talk about: 

14:00 – The surprising science of bitter taste receptors in your gut

19:00 – How Calocurb compares to Ozempic and Wegovy

26:25 – Hormonal influences on hunger (menstrual cycle, perimenopause, menopause)

28:30 – Why 70% of people are overweight in today’s food environment

34:50 – Safety guidelines for women, pregnancy, and breastfeeding

39:00 – How to time Calocurb for cravings, late-night snacking, and travel

44:30 – Why women in their luteal phase may benefit most

47:30 – Addressing childhood obesity and adolescent use of Calocurb

Questions answered in this episode: 

  • What are bitter taste receptors in the gut, and how do they control appetite?

  • How does Calocurb naturally stimulate satiety hormones compared to drugs like Ozempic?

  • Why does suppressing appetite with pharmaceuticals often lead to rebound hunger?

  • Can Calocurb support women during PMS, perimenopause, and menopause?

  • Is Calocurb safe for pregnant or breastfeeding women?

  • How can appetite regulation help with late-night snacking and emotional eating?

  • What role could natural solutions like Calocurb play in addressing childhood obesity?

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