Carolina Reis Oliveira, PhD and co-founder of OneSkin (code: BIOHACKINGBRITTANY), exposes why so many “anti-aging” products quietly inflame your skin, accelerate cellular aging, and wreck your barrier — and what a true longevity-first skincare routine looks like instead.
We unpack senescent “zombie cells”, exosome facials, NAD+ creams, rating apps like EWG and Yuka, and how to choose products that are both clean and clinically effective without overloading your skin. As a mom and longevity nerd, I also ask her how women can simplify their routines without sacrificing results, especially when we’re juggling babies, work, and sleep.
Join my 12 Holiday Rituals Giveaway for a chance to win part of $5,500+ USD in wellness prizes. Open until December 24th!
We talk about:
02:00 - Why OneSkin started by testing popular “anti-aging” creams on real human skin
10:35 - What senescent “zombie cells” are and why they act like rotten apples inside your skin
14:15 - Why OneSkin keeps its OS-01 peptide topical (not oral) and what that means for safety vs. supplements
17:45 - Exosome facials, plant stem cell exosomes, and how to tell if what’s in the vial is actually still active
19:15 - NAD, NMN, niacinamide and so-called “mitochondria” creams — what the data really shows on skin aging
25:55 - The kinds of clinical tests and lab data Carolina looks for before she’ll trust a formula
31:05 - Exactly where OneSkin fits into your routine with vitamin C, retinol, eye creams and exfoliants
34:05 - Non-comedogenic formulas, coconut oil breakouts and how OneSkin formulates for acne-prone skin
39:15 - How to actually use a gua sha for lymph drainage, jaw tension and lip lines
40:35 - The future of longevity: Shifting from “anti-aging” to extending women’s healthspan and vitality into our 70s and 80s
43:40 - Hormone therapy, prevention and why “just get used to it, you’re getting old” is a dangerous narrative
45:40 - How to spot longevity greenwashing in both skincare and supplements
Questions answered in this episode:
-
Why did OneSkin’s founders discover that many “anti-aging” products were actually inflaming and aging skin in the lab?
-
What are senescent “zombie cells,” and how do they silently sabotage your skin from the inside out?
-
How does clearing senescent cells improve both the look and function of your skin barrier as you age?
-
Why does Carolina see skin as a longevity organ and not just something to treat for wrinkles and pores?
-
Are exosomes and stem cell serums in skincare worth the money, and what are the stability + safety concerns?
-
What’s the real difference between NAD/NMN/niacinamide in your serum versus in your supplement stack?
-
How can you vet a skincare product for both cleanliness and efficacy without being a chemist?
-
Which clinical tests (instrument data, dermatologist grading, consumer studies) actually matter when you’re deciding what to buy?
-
Why can overloading your routine with retinoids, vitamin C, peels and 20 peptides make your skin more reactive?
-
How reliable are sites like EWG and Yuka and what are their biggest blind spots when it comes to full formulas?
-
Where does OneSkin fit if you already use vitamin C, retinol, eye creams, and weekly exfoliants and how should you layer it?
-
Is OneSkin comedogenic for acne-prone or sensitive skin, and what do they do differently in formulation?
-
How can tools like a lip mask and gua sha support lymph, lip lines and facial tension as part of a longevity routine?
Resources:
- Free gift: Download my hormone-balancing, fertility-boosting chocolate recipe.
- Explore my luxury retreats and wellness events for women.
- Shop my faves: Check out my Amazon storefront for wellness essentials.
- OneSkin’s website (code: BIOHACKINGBRITTANY) and Instagram
- Join my 12 Holiday Rituals Giveaway before December 24th
Let's connect:
- Instagram, TikTok, Facebook
- Shop my favorite health products
- Listen on Spotify, Apple Podcasts, YouTube Music