In this Q&A episode, we strip the science-speak out of longevity and hand you the practical takeaways.
I unpack spermidine, NRF2, sirtuins and NAD—three buzzwords that can actually become game-changing tools when you understand how they work inside a woman’s body.
I share the vetted products in my personal stack, free lifestyle hacks, and a quick framework to choose what suits your goals and genetics—so biohacking stays simple, empowering, and tailored to your life.
We talk about:
01:20 – Today’s hot-seat Q&A: Spermidine, NRF2, NAD, sirtuins, and stacking strategy
07:25 – What spermidine actually does: Autophagy without the fast (SpermidineLIFE code: BIOHACKINGBRITTANY)
09:30 – NRF2 pathway 101: Flipping your antioxidant “master switch”
13:10 – Natural NRF2 activators
18:20 – NAD decoded: Why your mitochondria runs on this co-enzyme
20:45 – Best—and worst—ways to raise NAD: NOVOS (code: BIOHACKINGBRITTANY)
23:30 – Sirtuins unlocked: Longevity genes that need NAD to work
25:00 – The synergy play: When stacking three pathways makes sense
27:10 – My personal protocol & dosing tips
Questions answered in this episode:
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What is spermidine, and how does it trigger autophagy?
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How does activating the NRF2 pathway boost detoxification and glutathione?
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What role does NAD play in mitochondrial energy production?
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What’s the relationship between NAD and the seven sirtuin “longevity genes”?
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Can spermidine, NRF2 activators, and NAD boosters be safely taken together?
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Which lifestyle habits (fasting, sauna, cold plunges) raise NAD naturally?
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How does Brittany decide which longevity supplements are worth the spend?
Sponsors:
- Swap restless nights for real recovery with Magnesium Breakthrough by BiOptimizers (code: BIOHACKINGBRITTANY) — the full-spectrum formula I trust for calmer nerves, balanced hormones, and deep, restorative sleep.
Resources:
- Trying to conceive? Join my Baby Steps Course to optimize your fertility with biohacking.
- Free gift: Download my hormone-balancing, fertility-boosting chocolate recipe.
- Explore my luxury retreats and wellness events for women.
- Shop my faves: Check out my Amazon storefront for wellness essentials.
- The DNA Blueprint episode with Kashif Khan
- Kid Gut Resilience: Birth, Stress & Health with Ara Katz of Seed
Let's connect:
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