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Genetics, Hormones, and Peptides: Decoding Women’s DNA for Fertility, Stress, and Longevity with Lindsey Strong

Genetics, Hormones, and Peptides: Decoding Women’s DNA for Fertility, Stress, and Longevity with Lindsey Strong

Lindsey Strong joins Brittany to decode how genetics, epigenetics, and key SNPs (think MTHFR, COMT, CYPs, nitric oxide) shape women’s hormones, stress, fertility, and recovery - and when peptides might actually help (or not) if you’re TTC, pregnant, or breastfeeding. 

We break down how to read a genetics report without fear, why no one has “perfect genes,” and how to translate SNPs into food, lifestyle, and supplement strategy. 

If you’re a woman ready to turn your DNA, hormones, and daily habits into a simple, evidence-informed plan - for steadier energy, better cycles, smarter fertility/pregnancy/breastfeeding choices, smoother perimenopause, and clarity on when (or if) peptides make sense - this episode is for you.

We talk about: 

08:00 - Genetics & women’s health basics and why “good/bad genes” is a myth

09:10 - How to read DNA reports; greens, yellows, reds as action guides

15:40 - Why many women’s symptoms are “cellular dysfunction,” not a tidy diagnosis

27:20 - Cortisol wiring: ACE variants + the “golden” COMT genotype nuance

37:10 - Nitric oxide: Circulation, energy, libido; breath-of-fire and beets

41:40 - Choline at midlife, cognition, lipids; prenatal relevance too

47:10 - Envirotoxins, UGT/glucuronidation, calcium-D-glucarate, and sauna vs supplements

50:00 - Peptides 101 + safety nuance for pregnancy & breastfeeding

55:20 - Favorites: GLP-1/“tirzepatide,” MOTS-C, SS-31, Epitalon for receptors/telomeres

59:00 - How to work with a practitioner; testing + peptide education options

Questions answered in this episode: 

  • How should women interpret “red/yellow/green” SNPs without spiraling?

  • Which SNPs most often impact cycles, PMS, and perimenopause? 

  • What do histamine SNPs actually look like symptom-wise (skin, gut, sleep, anxiety)?

  • Can your DNA predispose you to insulin resistance—and how do you act on that?

  • What’s practical about phase-1 CYP variants for meds, estrogen, THC metabolism?

  • How do nitric-oxide SNPs influence energy, brain fog, libido, and training?

  • Who needs more Choline (midlife cognition, lipids, pregnancy), and from where should you get it?

  • Sauna vs supplements vs travel reality: what actually reduces toxin burden?

  • Can you use peptides during pregnancy/breastfeeding?

  • Which peptides may support mitochondria, sleep, or receptor health?

Sponsors:

  • CaloCurb (get 10% OFF) is my go-to, 100% plant-based alternative to Ozempic—helping you feel full sooner, snack less, and finally trust your body again without needles, drugs, or yo-yo diets.
  • Reset stress on demand with Pulsetto (code: BIOHACKINGBRITTANY) - a neck-worn vagus-nerve stim that calms stress in ~4 minutes so you sleep better and feel calmer.

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